The Composition of the Chemicals, Antioxidants, and Anti-Microbial Agents on the Essential Oil of the Piper Species and Its Potential as A Natural Preservative: A Review
DOI:
https://doi.org/10.23960/jtep-l.v12i2.312-325Abstract
The production of safe food with a little to no artificial preservatives is the main and most important challenge for the food manufacturing industry. Increasing demand of using the safe preservatives has pushed the food industry to use the herbal or natural preservatives. The essential oil of the piper species consists of complex compounds like the monoterpene that has a power in the activity of the antioxidant and antibacterial. The object of research is the essential oil of piper species like the Piper nigrum, Piper betle, Piper retrofractum, Piper caninum, and Piper cubeba. The review methodology used in this research is the PRISMA flowchart (2020). PRISMA aims to identify the quality of papers and transparency of the number of articles. The objective of this research is to summarize the research related to the chemical content of the piper essential oil, the antioxidant and anti-microbe as the potential natural preservatives. The anti-microbe activity on the piper species shows the MIC score ranging from 1.5 to 12.8 mg/mL towards the standard of bacterial preservatives in preventing pathogens in foods. The essential oil of piper species has the higher antioxidant compared to the synthetic ones, like the BHA and BHT that have the score of IC <50 mg/mL. The essential oil of piper species has the GRAS certification and safe as an additive in foods.
Keywords: DPPH, Monoterpene, MIC, Sesquiterpene.
References
Ahmad, N., Fazal, H., Abbasi, B.H., Rashid, M., Mahmood, T., & Fatima, N. (2010). Efficient regeneration and antioxidant potential in regenerated tissues of Piper nigrum L. Plant Cell, Tissue and Organ Culture, 102(1), 129–134. https://doi.org/10.1007/s11240-010-9712-x
Akthar, M.S., Birhanu, G., & Demisse, S. (2014). Antimicrobial activity of Piper nigrum L. and Cassia didymobotyra L. leaf extract on selected food borne pathogens. Asian Pacific Journal of Tropical Disease, 4(S2), S911–S919. https://doi.org/10.1016/S2222-1808(14)60757-X
Alminderej, F., Bakari, S., Almundarij, T.I., Snoussi, M., Aouadi, K., & Kadri, A. (2020). Antioxidant activities of a new chemotype of Piper cubeba L. fruit essential oil (methyleugenol/eugenol): In silico molecular docking and admet studies. Plants, 9(11), 1–18. https://doi.org/10.3390/plants9111534
Andriana, Y., Xuan, T.D., Quy, T.N., Tran, H.D., & Le, Q.T. (2019). Biological activities and chemical constituents of essential oils from Piper cubeba Bojer and Piper nigrum L. Molecules, 24(10), 1876. https://doi.org/10.3390/molecules24101876
Annegowda, H.V., Tan, P.Y., Mordi, M.N., Ramanathan, S., Hamdan, M.R., Sulaiman, M.H., & Mansor, S.M. (2013). TLC-Bioautography-Guided Isolation, HPTLC and GC-MS-assisted analysis of bioactives of Piper betle leaf extract obtained from various extraction techniques: In vitro evaluation of phenolic content, antioxidant and antimicrobial activities. Food Analytical Methods, 6(3), 715–726. https://doi.org/10.1007/s12161-012-9470-y
Bagheri, H., Manap, M.Y.A., & Solati, Z. (2014). Antioxidant activity of Piper nigrum L. essential oil extracted by supercritical CO2 extraction and hydro-distillation. Talanta, 121, 220–228. https://doi.org/10.1016/j.talanta.2014.01.007
Basak, S., & Guha, P. (2017). Betel leaf (Piper betle L.) essential oil microemulsion: Characterization and antifungal activity on growth, and apparent lag time of Aspergillus flavus in tomato paste. LWT, 75, 616–623. https://doi.org/10.1016/j.lwt.2016.10.021
Bhanja, S.K., Maity, P., Rout, D., Sen, I.K., & Patra, S. (2022). A xylan from the fresh leaves of Piper betle: Structural characterization and studies of bioactive properties. Carbohydrate Polymers, 291, 119570. https://doi.org/10.1016/j.carbpol.2022.119570
Cacho, J.I., Campillo, N., Viñas, P., & Hernández-Córdoba, M. (2016). Determination of synthetic phenolic antioxidants in edible oils using microvial insert large volume injection gas-chromatography. Food Chemistry, 200, 249–254. https://doi.org/10.1016/j.foodchem.2016.01.026
Chen, C.J., Tseng, Y.H., Chu, F.H., Wen, T.Y., Cheng, W.W., Chen, Y.T., Tsao, N.W., & Wang, S.Y. (2012). Neuropharmacological activities of fruit essential oil from Litsea cubeba Persoon. Journal of Wood Science, 58(6), 538–543. https://doi.org/ 10.1007/s10086-012-1277-3
da Silva, J.K., da Trindade, R., Alves, N.S., Figueiredo, P.L., Maia, J.G.S., & Setzer, W.N. (2017). Essential oils from neotropical piper species and their biological activities. Int J Mol Sci, 18(12), 2571. https://doi.org/10.3390/IJMS18122571
Das, S., Sandeep, I.S., Mohapatra, P., Kar, B., Sahoo, R.K., Subudhi, E., Nayak, S., & Mohanty, S. (2022). A comparative study of essential oil profile, antibacterial and antioxidant activities of thirty Piper betle landraces towards selection of industrially important chemotypes. Industrial Crops and Products, 187(Part A), 115289. https://doi.org/10.1016/j.indcrop.2022.115289
Fan, R., Qin, X.W., Hu, R.S., Hu, L.S., Wu, B.D., & Hao, C.Y. (2020). Studies on the chemical and flavour qualities of white pepper (Piper nigrum L.) derived from grafted and non-grafted plants. European Food Research and Technology, 246(12), 2601–2610. https://doi.org/10.1007/s00217-020-03600-1
Freires, I.A., Denny, C., Benso, B., de Alencar, S.M., & Rosalen, P.L. (2015). Antibacterial activity of essential oils and their isolated constituents against cariogenic bacteria: A systematic review. Molecules, 20(4), 7329–7358. https://doi.org/10.3390/molecules20047329
Gyawali, R., & Ibrahim, S.A. (2014). Natural products as antimicrobial agents. Food Control, 46, 412–429. https://doi.org/10.1016/j.foodcont.2014.05.047
Hao, C.Y., Fan, R., Ribeiro, M.C., Tan, L.H., Wu, H.S., Yang, J.F., Zheng, W.Q., & Yu, H. (2012). Modeling the potential geographic distribution of black pepper (Piper nigrum) in Asia using GIS tools. Journal of Integrative Agriculture, 11(4), 593–599. https://doi.org/10.1016/S2095-3119(12)60046-X
Hutami, R., Nur’utami, D.A., & Joana, A. (2021). Antioxidant activity, sensory, chemical, and microbiology characteristics of Muntok white pepper (Piper nigrum Linn.) hard candy. Indonesian . Indonesian Journal of Applied Research (IJAR), 2(1), 147–27. https://doi.org/10.30997/ijar.v2i1.98
Hyldgaard, M., Mygind, T., & Meyer, R.L. (2012). Essential oils in food preservation: Mode of action, synergies, and interactions with food matrix components. Frontiers in Microbiology, 3(12), 1-24. https://doi.org/10.3389/fmicb.2012.00012
Irshad, S., Ashfaq, A., Muazzam, A., & Yasmeen, A. (2017). Antimicrobial and anti-prostate cancer activity of turmeric (Curcuma longa L.) and black pepper (Piper nigrum L.) used in typical Pakistani cuisine. Pakistan Journal of Zoology, 49(5), 1665–1669. https://doi.org/10.17582/journal.pjz/2017.49.5.1665.1669
Kang, G.Q., Duan, W.G., Lin, G.S., Yu, Y.P., Wang, X.Y., & Lu, S.Z. (2019). Synthesis of bioactive compounds from 3-carene (II): Synthesis, antifungal activity and 3D-QSAR study of (Z)- and (E)-3-caren-5-one oxime sulfonates. Molecules, 24(3), 477. https://doi.org/10.3390/molecules24030477
Karak, S., Acharya, J., Begum, S., Mazumdar, I., Kundu, R., & De, B. (2018). Essential oil of Piper betle L. leaves: Chemical composition, anti-acetylcholinesterase, anti-β-glucuronidase and cytotoxic properties. Journal of Applied Research on Medicinal and Aromatic Plants, 10, 85–92. https://doi.org/10.1016/j.jarmap.2018.06.006
Keerthana, C., & Narayanan, R.B. (2021). Identification and characterization of pediococcus species from Piper betle (Betel) leaves. Current Microbiology, 78(1), 198–205. https://doi.org/10.1007/s00284-020-02270-2
Li, Y. xin, Zhang, C., Pan, S., Chen, L., Liu, M., Yang, K., Zeng, X., & Tian, J. (2020). Analysis of chemical components and biological activities of essential oils from black and white pepper (Piper nigrum L.) in five provinces of southern China. LWT, 117, 108644. https://doi.org/10.1016/j.lwt.2019.108644
Liu, H., Zheng, J., Liu, P., & Zeng, F. (2018). Pulverizing processes affect the chemical quality and thermal property of black, white, and green pepper (Piper nigrum L.). Journal of Food Science and Technology, 55(6), 2130–2142. https://doi.org/10.1007/s13197-018-3128-8
Madhumita, M., Guha, P., & Nag, A. (2019). Extraction of betel leaves (Piper betle L.) essential oil and its bio-actives identification: Process optimization, GC-MS analysis and anti-microbial activity. Industrial Crops and Products, 138, 111578. https://doi.org/10.1016/j.indcrop.2019.111578
Makpol, S., Yeoh, T.W., Ruslam, F.A.C., Arifin, K.T., & Yusof, Y.A.M. (2013). Comparative effect of Piper betle, Chlorella vulgaris and tocotrienol-rich fraction on antioxidant enzymes activity in cellular ageing of human diploid fibroblasts. BMC Complementary and Alternative Medicine, 13, 210. https://doi.org/10.1186/1472-6882-13-210
Morais-Braga, M.F.B., Leal, A.L.A.B., de Oliveira, A.H., Carneiro, J.N.P., dos Santos, A.T.L., Sales, D.L., Fonseca, V.J.A., Rocha, J.E., de Freitas, T.S., Campina, F.F., do Socorro Costa, M., Pereira-Junior, F.N., do Amaral, W., Rebelo, R.A., da Silva, L.E., Ribeiro-Filho, J., & Coutinho, H.D.M. (2022). Chemical characterization and antimicrobial potential of the essential oil obtained from the leaves of Piper xylosteoides (Kunth) Steud. South African Journal of Botany, 151(Part B), 328-336. https://doi.org/10.1016/j.sajb.2022.03.017
Mothana, R.A.A., Mothana, R.A., Al-Said, M.S., Raish, M., Khaled, J.M., Alharbi, N.S., Alatar, A., Ahmad, A., Al-Sohaibani, M., Al-Yahya, M., & Rafatullah, S. (2017). Chemical composition, anti-inflammatory and antioxidant activities of the essential oil of Piper cubeba L. Romanian Biotechnological Letters, 22(2), 12366.
Nereyda, E., & Sauceda, R. (2011). Uso de agentes antimicrobianos naturales en la conservación de frutas y hortalizas. Ra Ximhai, 7(1), 153-170. http://dx.doi.org/10.35197/rx.07.01.2011.14.er
Nikolić, M., Stojković, D., GlamoÄlija, J., Ćirić, A., Marković, T., Smiljković, M., & Soković, M. (2015). Could essential oils of green and black pepper be used as food preservatives? Journal of Food Science and Technology, 52(10), 6565–6573. https://doi.org/10.1007/s13197-015-1792-5
Sazwi, N.N., Nalina, T., & Rahim, Z.H.A. (2013). Antioxidant and cytoprotective activities of Piper betle, Areca catechu, Uncaria gambir and betel quid with and without calcium hydroxide. BMC Complement Altern Med., 13, 351. https://doi.org/10.1186/1472-6882-13-351
Pawar, H.A., Shenoy, A.V, Narawade, P.D., Soni, P.Y., Shanbhag, P.P., & Rajal, V.A. (2011). Preservatives from nature: A review. International Journal of Pharmaceutical and Phytopharmacological Research, 1(2), 78-88.
Prakash, B., Kujur, A., Yadav, A., Kumar, A., Singh, P.P., & Dubey, N.K. (2018). Nanoencapsulation: An efficient technology to boost the antimicrobial potential of plant essential oils in food system. Food Control, 89, 1–11. https://doi.org/10.1016/j.foodcont.2018.01.018
Raut, J.S., & Karuppayil, S.M. (2014). A status review on the medicinal properties of essential oils. Industrial Crops and Products, 62, 250–264). https://doi.org/10.1016/j.indcrop.2014.05.055
Ribeiro-Santos, R., Andrade, M., Melo, N.R. de, & Sanches-Silva, A. (2017). Use of essential oils in active food packaging: Recent advances and future trends. Trends in Food Science and Technology, 61, 132–140. https://doi.org/10.1016/j.tifs.2016. 11.021
Rukayadi, Y., Lau, K.Y., Zainin, N.S., Zakaria, & Abas, F. (2013). Screening antimicrobial activity of tropical edible medicinal plant extracts against five standard microorganisms for natural food preservative. International Food Research Journal, 20(5), 2905-2910 .
Saini, A., Pandey, A., Sharma, S., Suradkar, U.S., Ambedkar, Y.R., & Meena, P. (2021). Evaluation of antioxidant potential of betel (Piper betel) leaves extract. International Research Journal of Chemistry, 34, 1–8.
Salehi, B., Zakaria, Z.A., Gyawali, R., Ibrahim, S.A., Rajkovic, J., Shinwari, Z.K., Khan, T., Sharifi-Rad, J., Ozleyen, A., Turkdonmez, E., Valussi, M., Tumer, T.B., Fidalgo, L.M., Martorell, M., & Setzer, W.N. (2019). Piper species: A comprehensive review on their phytochemistry, biological activities and applications. Molecules, 24(7), 1364. https://doi.org/10.3390/molecules24071364
Salleh, W.M.N.H.W., Ahmad, F., Yen, K.H., & Sirat, H.M. (2011). Chemical compositions, antioxidant and antimicrobial activities of essential oils of Piper caninum Blume. International Journal of Molecular Sciences, 12(11), 7720–7731. https://doi.org/10.3390/ijms12117720
Sarma, C., Rasane, P., Kaur, S., Singh, J., Singh, J., Gat, Y., Garba, U., Kaur, D., & Dhawan, K. (2018). Antioxidant and antimicrobial potential of selected varieties of Piper betle L. (betel leaf). Anais Da Academia Brasileira de Ciencias, 90(4), 3871–3878. https://doi.org/10.1590/0001-3765201820180285
Sharifi-Rad, M., Roberts, T.H., Matthews, K.R., Bezerra, C.F., Morais-Braga, M.F.B., Coutinho, H.D.M., Sharopov, F., Salehi, B., Yousaf, Z., Sharifi-Rad, M., del Mar Contreras, M., Varoni, E.M., Verma, D.R., Iriti, M., & Sharifi-Rad, J. (2018). Ethnobotany of the genus Taraxacum—Phytochemicals and antimicrobial activity. Phytotherapy Research, 32(11), 2131–2145). https://doi.org/10.1002/ptr.6157
Singh, S., Kapoor, I.P.S., Singh, G., Schuff, C., de Lampasona, M.P., & Catalan, C.A.N. (2013). Chemistry, antioxidant and antimicrobial potentials of white pepper (Piper nigrum L.) essential oil and oleoresins. Proceedings of the National Academy of Sciences India Section B - Biological Sciences, 83(3), 357–366. https://doi.org/10.1007/s40011-012-0148-4
Singh, T.P., Chauhan, G., Agrawal, R.K., & Mendiratta, S.K. (2019). In vitro study on antimicrobial, antioxidant, FT-IR and GC–MS/MS analysis of Piper betle L. leaves extracts. Journal of Food Measurement and Characterization, 13(1), 466–475. https://doi.org/10.1007/s11694-018-9960-8
Takahashi, M., Oe, M., Arakaki, M., & Wada, K. (2020). Effect of leaf growth on the taste and aroma functions and antioxidant characteristics of hihatsumodoki (Piper retrofractum Vhal) leaf. Journal of Food Measurement and Characterization, 14(2), 1002–1011. https://doi.org/10.1007/s11694-019-00349-4
Tongnuanchan, P., & Benjakul, S. (2014). Essential oils: Extraction, bioactivities, and their uses for food preservation. Journal of Food Science, 79(7), R1231-R1249. https://doi.org/10.1111/1750-3841.12492
Valle, D.L., Cabrera, E.C., Puzon, J.J.M., & Rivera, W.L. (2016). Antimicrobial activities of methanol, ethanol and supercritical CO2 extracts of Philippine Piper betle L. on clinical isolates of gram positive and gram negative bacteria with transferable multiple drug resistance. PLoS ONE, 11(1), e0146349. https://doi.org/10.1371/journal.pone.0146349
Wasito, H., Ekowati, H., & Hayati, F.F. (2011). In vitro antioxidant activity of Zingiber officinale, Piper retrofractum, and their combinations. Indonesian Journal of Cancer Chemoprevention, 2(3), 295-298. http://dx.doi.org/10.14499/indonesianjcanchemoprev2iss3pp295-298
Yu, H.H., Kim, Y.J., Park, Y.J., Shin, D.M., Choi, Y.S., Lee, N.K., & Paik, H.D. (2020). Application of mixed natural preservatives to improve the quality of vacuum skin packaged beef during refrigerated storage. Meat Science, 169, 108219. https://doi.org/10.1016/j.meatsci.2020.108219
Zarai, Z., Boujelbene, E., ben Salem, N., Gargouri, Y., & Sayari, A. (2013). Antioxidant and antimicrobial activities of various solvent extracts, piperine and piperic acid from Piper nigrum. LWT Food Science and Technology, 50(2), 634–641. https://doi.org/10.1016/j.lwt.2012.07.036
Zhang, C., Zhao, J., Famous, E., Pan, S., Peng, X., & Tian, J. (2021). Antioxidant, hepatoprotective and antifungal activities of black pepper (Piper nigrum L.) essential oil. Food Chemistry, 346, 128845. https://doi.org/10.1016/j.foodchem.2020.128845
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